Sperm DNA fragmentation index influences assisted reproductive technology outcome: a global systemic review and thorough meta-analysis
نویسندگان
چکیده
منابع مشابه
Consequences of sperm DNA fragmentation for assisted reproductive technology
The possession of offspring is the most important human biological goal, which conditions the survival of the human species. The problem of the lack of offspring is a phenomenon concerning approximately 15% of married couples in Poland. In a half of the cases, the causative agent is the male factor infertility problem. It is considered that in approximately 20% of patients with idiopathic infer...
متن کاملSperm deoxyribonucleic acid fragmentation as a prognostic indicator of assisted reproductive technology outcome.
OBJECTIVE To examine sperm DNA fragmentation in semen used for assisted reproduction procedures to establish this factor's prognostic role in fertilization rate, embryo development, pregnancy rate, and outcome. DESIGN Prospective study. SETTING Department of Medicine and Biology of Reproduction of the Edouard Herriot Hospital in Lyon, France. PATIENT(S) 322 couples, divided into 88 cycles...
متن کاملMeasuring Sperm DNA Fragmentation and Clinical Outcomes of Medically Assisted Reproduction: A Systematic Review and Meta-Analysis
Sperm DNA fragmentation has been associated with reduced fertilization rates, embryo quality, pregnancy rates and increased miscarriage rates. Various methods exist to test sperm DNA fragmentation such as the sperm chromatin structure assay (SCSA), the sperm chromatin dispersion (SCD) test, the terminal deoxynucleotidyl transferase mediated deoxyuridine triphosphate nick end labelling (TUNEL) a...
متن کاملSperm capacitation: effect of assisted reproductive technology
The past several decades witnessed great advances in the Andrology Sciences in humans. This certainly increased our knowledge in understanding the process of spermatogenesis, capacitation, and fertilization. Much of this work has been acquired from animal experimentation (1, 2, 3). However, the introduction of assisted reproductive technology improved our understanding of the process of fertili...
متن کاملWhether G-CSF administration has beneficial effect on the outcome after assisted reproductive technology? A systematic review and meta-analysis
BACKGROUND Previous studies have explored the effect of granulocyte colony stimulating factor (G-CSF) administration on the outcome of assisted reproductive technology (ART), and came into controversial conclusions. The present meta-analysis aims to assess whether G-CSF administration has beneficial effect on the outcome after ART. METHOD The electronic databases Pubmed, Embase and Google Sch...
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ژورنال
عنوان ژورنال: Fertility and Sterility
سال: 2017
ISSN: 0015-0282
DOI: 10.1016/j.fertnstert.2017.07.247